Pillar 04

Advanced Medical & Regenerative Optimization

A responsible, educational, exploratory engagement with the most sensitive and most rapidly advancing field in human optimization. Peptides, TRT, HGH, stem cells, regenerative medicine, gene therapies, mitochondrial science, epigenetics, biological age work, future medicine. Working log, not product line. Singapore HSA compliant by default. Pieces pass a medical reviewer before publication.

Reading · 2 entries

2026.05.10

Review

8 min

BPC 157 at 250mcg, after eight weeks

A peptide protocol for tendon recovery. n=1, supervised, Singapore HSA compliant compounding.

2026.05.16

Essay

7 min

Longevity, at the tempo of a decade

Notes on a private practice — and on the discipline of writing about it without overclaiming.

The Stack · 4 tools

What I’m currently using in this pillar. Each links to a full review with mechanism, evidence, and verdict.

Affiliate disclosure. The Human Upgrade may earn a commission on purchases made through links on this page. We only recommend tools we’ve tested or would use ourselves. Disclosure does not change verdicts.

Hormone optimization

TRT, clinically supervised

Clinic, Singapore

On protocol for 18 months. Quarterly bloods. Working with an endocrinologist. n=1, supervised.

$$$$Tested 18 months

Read the review Buy at Clinic →

Peptide

BPC 157, 250mcg

Compounding pharmacy Rx

Eight week cycle for tendon recovery. Singapore HSA compliant compounding. Honest about evidence limits.

$$$Tested 8 weeks

Read the review Buy at Clinic →

Biological age

TruDiagnostic OMICm Age

TruDiagnostic

Annual epigenetic age test. Useful trend data; not a verdict. The test is the diary, not the destination.

$$$Tested 2 years

Read the review Buy at TruDiagnostic →

VO2 max testing

Quarterly VO2 max + lactate

Sports clinic

Best longevity biomarker available. Quarterly is overkill; semi annual is right.

$$$Tested 3 years

Read the review Buy at Clinic →

A note on this pillar

Nothing on this pillar constitutes medical advice. Alvin Tan is a functional health coach in training, not a licensed clinician. Every entry passes a Singapore licensed medical reviewer before publication. The Human Upgrade is a publication, not a medical practice. Any reader considering interventions in this field should consult a qualified clinician in their own jurisdiction.