Profhilo at six months.

Profhilo isn’t a filler. It’s a stabilised hyaluronic acid that acts as a bio stimulator — injected at specific anatomical points (the BAP technique), it triggers the skin’s own collagen and elastin production over weeks rather than instantly “filling” anything. That distinction matters. Most of the bad outcomes I’ve seen in this category are from clinicians or clients treating it as a filler.

Stabilised hyaluronic acid, injected into the deeper dermis at five points per side of the face. Two sessions, one month apart. Results compound over six to eight weeks.

The high molecular weight HA stimulates fibroblasts — the cells that produce collagen and elastin. Over weeks, the skin’s structural matrix is rebuilt rather than padded. Hydration improves first; firmness lags by four to six weeks.

Multiple peer reviewed studies (Beatini et al. 2022, Sparavigna et al. 2020) show measurable improvements in skin hydration, elasticity, and dermal density at 8–16 weeks. The trials are industry funded, but the effect is consistent. Honest summary: bio stimulation works; magnitude depends on baseline.

Adults in their 30s and 40s with skin quality concerns (texture, mild laxity, dullness) rather than volume loss. Best as part of a maintenance protocol, not as a transformation.

Anyone seeking a visible filler effect — this is the wrong tool. Anyone with active skin infection or autoimmune conditions affecting connective tissue. Anyone with unrealistic expectations of magnitude.

Two sessions, one month apart. Booster every nine months. Clinic in Singapore with an aesthetic doctor who’s done several hundred treatments. The clinician matters more than the product.

Skin hydration noticeably improved by week three (subjective, photo documented). Texture refined by week six. Mild jawline definition by month four. What didn’t shift: deep lines, visible volume loss, anything Botox or filler would address. This is a maintenance tool, not a corrective one.

— Alvin